Fig. 6: Pkd2l1 deletion promotes pericentral canal vacuolar degeneration and glial scar formation following SCI. | Cell Death Discovery

Fig. 6: Pkd2l1 deletion promotes pericentral canal vacuolar degeneration and glial scar formation following SCI.

From: Pkd2l1 deletion inhibits the neurogenesis of cerebrospinal fluid-contacting neurons and impedes spinal cord injury repair

Fig. 6

a H&E staining showed that Pkd2l1−/− mice had more pericentral canal vacuolar degeneration after SCI. b, c Masson staining conducted on the transverse section of spinal cord tissue at the thoracic 10 (T10) level revealed that Pkd2l1−/− mice exhibited pronounced accumulation of collagen fibers, leading to the formation of glial scars around the central canal following SCI (n = 6). *p < 0.05. Data are presented as the mean ± SD. Scale bars, 100 µm.

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