Fig. 7: Related schematic diagram of this study. | Cell Death Discovery

Fig. 7: Related schematic diagram of this study.

From: miR-139-5p activates ferroptosis by inhibiting the expression of HMG-CoA reductase to inhibit the progression of glioma

Fig. 7

The schematic diagram briefly describes the process of cholesterol synthesis and the specific molecular mechanism by which this pathway regulates the progression of ferroptosis. In addition, miR-139-5p and SIM synergistically inhibited the enzymatic activity of HMGCR to participate in the regulation of cholesterol biosynthesis and cell ferroptosis. Created with www.figdraw.com.

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