Fig. 2: Presence of small clusters of cells with LGR5 expression in resected tumor tissue following chemotherapy.

A Representative image for LGR5 expression in a small cluster in Case 1. Arrowheads indicate LGR5-expression in glandular structure. Scale bar: 100 μm. B H-score of LGR5 for 12 cases. C Representative image for LGR5 expression in a small cluster (arrow) in Cases 2–4. Scale bar: 100 μm.