Fig. 2: Cell death following light-induced photoreceptor degeneration.
From: Illuminating photoreceptors: TGFβ signaling modulates the severeness of retinal degeneration
Mid-horizontal sections of TdT-mediated dUTP-biotin nick end (TUNEL)-labeled (green, arrowheads) control and 6 h following light damage retinae (A). Detailed magnification (B) Cell nuclei were stained with DAPI (blue). C Total number of TUNEL-positive cells per section stretching through the optic nerve head (control n = 2 mean: 2.5 ± 1.5 (SEM); light damage n = 5 mean: 42.6 ± 5.5 (SEM); P = 0.0075; t-test. OS ora serrata, ON optic nerve, INL inner nuclear layer, ONL outer nuclear layer.
