Fig. 5: Regulatory interactions among AMPK, mTOR, and GFPT during acute and prolonged nutrient stress.
From: Exploring the metabolic signaling network of GFPT in cancer
Short nutrient starvation potentially inhibits GFPT1 directly via AMPK. In prolonged nutrient stress, GFPT1 activity is potentially maintained directly by mTORC2 and indirectly by AMPK.
