Fig. 8: Comparative pan-cancer expression and tumor stage correlation of GFPT1 and GFPT2.
From: Exploring the metabolic signaling network of GFPT in cancer
A Comparative gene expression analysis of GFPT1 and GFPT2 across multiple TCGA tumor types was performed using the Gene Expression Profiling Interactive Analysis (GEPIA) tool [218]. Expression values are represented as Z-scores of the median Log2(TPM + 1) across tumor samples for each cancer type. B Correlation analysis between GFPT1 and GFPT2 expression levels and tumor stage across TCGA cancers was conducted using TIMER2.0 [219]. The heatmap displays the normalized regression coefficients derived from a Cox proportional hazards model for each gene (GFPT1 or GFPT2), indicating their association with tumor stage.
