Fig. 1: SLC25A10 is highly expressed in the tissues of patients with cervical cancer.

We conducted Gene Set Enrichment Analysis (GSEA) using the Hallmarks gene set and identified numerous pathways significantly associated with cervical cancer (p-value ≤ 0.05). Among these, the SLC25 family gene set was significantly enriched (P = 0.02995) and ranked third among the upregulated Hallmark pathways (A). TCGA database analysis revealed that SLC25A10 expression was upregulated in cervical cancer (http://gepia.cancer-pku.cn) (B). mRNA and protein measurements were performed on cervical cancer tissue (“T”) and matched normal cervical epithelial tissue (“N”) from 12 (n = 12) patients with primary cervical cancer, and the results were quantified (C, D). Three representative SLC25A10-stained images of cervical cancer tissues and matched paracancerous cervical epithelial tissues, including highly differentiated G1, moderately differentiated G2, and poorly differentiated G3 tissues are shown (E). The correlation between SLC25A10 expression and the degree of tumor differentiation was statistically analyzed (F). * Compared with “T”, P < 0.05. Scale =100 µm.