Fig. 3: Anti-CD20 reverses the protective effect of RMT1-10 in myocardial IRI. | Cell Death Discovery

Fig. 3: Anti-CD20 reverses the protective effect of RMT1-10 in myocardial IRI.

From: The effect of TIM1+ Breg cells in myocardial ischemia-reperfusion injury

Fig. 3

A The myocardial infarction volume, as determined by TTC in the IRI, IRI + RMT1-10, and Anti-CD20 + IRI + RMT1-10 groups. B, C TUNEL and HE staining for myocardial cell apoptosis and changes in cardiomyocyte morphology in the IRI, IRI + RMT1-10, and Anti-CD20 + IRI + RMT1-10 groups. D Electron microscopy analysis of the cardiomyocyte structure in the IRI, IRI + RMT1-10, and Anti-CD20 + IRI + RMT1-10 groups. ***P < 0.001 vs. IRI, ###P < 0.001 vs. IRI + RMT1-10. E ELISA, LDH assays, and cTnT/I detection of the levels of CK-MB, LDH, and cTnT/I in serum. **P < 0.01,***P < 0.001 vs. IRI, ###P < 0.001 vs. IRI + RMT1-10.

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