Fig. 1: SSD exerted potent anti-tumor growth efficacy in multiple cancer types in vitro. | Cell Death Discovery

Fig. 1: SSD exerted potent anti-tumor growth efficacy in multiple cancer types in vitro.

From: Saikosaponin‑D triggers cancer cell death by targeting the PIM1/c-Myc axis to reprogram oncogenic alternative splicing

Fig. 1: SSD exerted potent anti-tumor growth efficacy in multiple cancer types in vitro.The alternative text for this image may have been generated using AI.

A Characters of Radix Bupleuri and the structures of SSs, including SSA, SSB1, SSB2, SSC, and SSD. Cell viability was determined with CCK-8 assays after different gastric cancer cells (B), prostate cancer cells (C), and colorectal cancer cells (D) were treated with Vehicle or SSD (10 μM) for 48 h. E CCK-8 assays were performed to determine cell viability after gastric cancer cells were treated with different dosages of SSD for 48 h. F The cell confluence was recorded with a microscope after gastric cancer cells were treated with different dosages of SSD for 48 h, and the relative cell confluence was calculated with image J. H, I The cell viability and cell growth of prostate cancer were determined with CCK-8 assays (G) and cell confluence analysis, respectively. *, p ≤ 0.05, **, p ≤ 0.01.

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