Fig. 3: Effects of overexpressing or inhibiting miR-122-5p in Exosomes on renal function and EMT markers in UUO mice. | Cell Death Discovery

Fig. 3: Effects of overexpressing or inhibiting miR-122-5p in Exosomes on renal function and EMT markers in UUO mice.

From: Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α

Fig. 3

A Flow diagram of exosomes injected into the tail vein of UUO mice; B The levels of miR-122-5p miRNA in kidney tissue were detected by quantitative polymerase chain reaction (qPCR); C The levels of creatinine in mice serum were determined by a biochemical analyzer; D The levels of blood urea nitrogen in mice serum were determined by a biochemical analyzer; E The expression levels of α-SMA and E-cadherin in kidney tissue were detected by western blotting; F Relative expression levels of α-SMA in renal tissues; G. Relative expression levels of E-cadherin in renal tissues. Results are shown as mean ± SD for six individual experiments. *P < 0.05, **P < 0.01.

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