Fig. 6: Tubule cell-derived exosomal miR-122-5p regulates fibroblasts via HIF-1α through the TGF-β1/Smad in vitro. | Cell Death Discovery

Fig. 6: Tubule cell-derived exosomal miR-122-5p regulates fibroblasts via HIF-1α through the TGF-β1/Smad in vitro.

From: Exosomal miR-122-5p from tubular cells ameliorates renal interstitial fibrosis by regulating fibroblasts via HIF-1α

Fig. 6

A The expression of HIF-1α, Smad2, Phospho-SMAD2 (Ser465/Ser467), Smad3, Phospho-SMAD3 (Ser423/425), and Smad7 in NRK-49F cells were detected by western blotting; B Relative expression levels of HIF-1α; C Relative expression levels of Smad2; D Relative expression levels of Phospho-SMAD2 (Ser465/Ser467); E Relative expression levels of Smad3; F Relative expression levels of Phospho-SMAD3 (Ser423/425); G Relative expression levels of Smad7. Results are shown as mean ± SD for three individual experiments. **P < 0.01.

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