Fig. 5: Intercellular networks in PT and MLN revealed by CellChat. | Cell Death Discovery

Fig. 5: Intercellular networks in PT and MLN revealed by CellChat.

From: Single-cell and spatial dissection of necroptosis spatiotemporal evolution driving lymph node metastasis in gastric cancer

Fig. 5: Intercellular networks in PT and MLN revealed by CellChat.The alternative text for this image may have been generated using AI.

A The bar chart illustrates the number and strength of intercellular interactions in the MLN and PT. The heat maps show the differences in the intensity (B) and quantity (C) of intercellular interactions between gastric cancer tumors and lymph nodes. D Bubble plots illustrate the significantly differentially expressed ligand-receptor pairs between lymph nodes and tumors. The color of each dot indicates the communication probability, while the size of the dot represents the computed p-value. Different cell groups are depicted in distinct colors. Empty spaces signify a communication probability of zero. p-values are computed from a two-sided permutation test. E The chord diagram depicts the inferred intercellular communication network of MIF signaling in metastatic lymph nodes and tumor tissues. Arc length represents the number of cells in each cell group and edge width represents the communication probability.

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