Fig. 3: TKT promotes RCC metastasis in vivo. | Cell Death Discovery

Fig. 3: TKT promotes RCC metastasis in vivo.

From: TKT drives renal cell carcinoma progression through metabolic reprogramming and synergistic interaction with PKM2

Fig. 3: TKT promotes RCC metastasis in vivo.The alternative text for this image may have been generated using AI.

A Schematic representation of the experimental protocol for establishing a mouse tail vein lung metastasis model using vector/TKT-overexpressing ACHN-luc cells. B, C Lung bioluminescence imaging and statistical analysis of metastatic burden across different groups. D Representative Hematoxylin and Eosin (H&E)-stained lung sections of different groups are shown. E Quantification of lung metastatic nodules at week 4. F Ki-67 IHC analysis in the TKT-overexpressing lung metastasis model, with quantification of Ki-67-positive cells. *P < 0.05, **P < 0.01, ***P < 0.001.

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