Fig. 6: Regulation of TKT to aerobic glycolysis is dependent on PKM2. | Cell Death Discovery

Fig. 6: Regulation of TKT to aerobic glycolysis is dependent on PKM2.

From: TKT drives renal cell carcinoma progression through metabolic reprogramming and synergistic interaction with PKM2

Fig. 6: Regulation of TKT to aerobic glycolysis is dependent on PKM2.The alternative text for this image may have been generated using AI.

A Representative images from Immunoprecipitation-Mass Spectrometry (IP-MS) analysis, demonstrating TKT-PKM2 interaction. B TKT coimmunoprecipitates with PKM2 in ACHN. C Western blot confirming PKM2 knockdown in control and TKT-overexpressing 786-O/ACHN cells. D–F Regulation of TKT to aerobic glycolysis is dependent on PKM2. *P < 0.05, **P < 0.01, ***P < 0.001.

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