Fig. 8: Schematic diagram of the study.
From: LBX2 promotes colorectal cancer progression via the glycosylation and lactylation positive feedback
LBX2 transcriptionally regulates GFPT2, modulating O-GlcNAcylation and Raptor T700 glycosylation in CRC cells, which alters mTORC1 activity, forming a regulatory axis with histone lactylation that promotes LBX2 upregulation.
