Fig. 2: RNA-seq analysis for primary chondrocytes with PFKFB3 knockdown and overexpression. | Cell Death Discovery

Fig. 2: RNA-seq analysis for primary chondrocytes with PFKFB3 knockdown and overexpression.

From: The glycolytic enzyme PFKFB3 alleviates DNA damage and chondrocyte senescence in osteoarthritis

Fig. 2

a Heatmap showing the top 100 differentially expressed genes (DEGs) in primary mouse chondrocytes transfected with siPFKFB3. b Heatmap showing the top 100 DEGs in primary mouse chondrocytes transfected with lenti-PFKFB3. c Gene Set Enrichment Analysis (GSEA) associated with DNA damage response and d cellular senescence in PFKFB3-knockdown chondrocytes.

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