Fig. 5: Analysis of RNA-seq differentially expressed genes and GSEA in patients with different treatments. | Cell Death Discovery

Fig. 5: Analysis of RNA-seq differentially expressed genes and GSEA in patients with different treatments.

From: GM-CSF improves the receptivity of thin endometrium by promoting glandular and stromal cell proliferation in mice and humans

Fig. 5

A The correlation between the GM-CSF and Saline groups, the Spearman correlation coefficients are also shown. B Volcano plot shows 220 upregulated and 84 downregulated differentially expressed genes (DEGs) (p < 0.05 and log2 fold change | > 1) in endometrium samples from GM-CSF (n = 3) and Saline (n = 3) groups. C, D Significantly enriched GO terms in the biological process (BP) category associated with up (red) and downregulated (blue) mRNAs in the GM-CSF group, respectively. E GSEA enrichment in the negative regulation of the cell cycle process. F, G Network diagram of differentially expressed genes and endometrium-related genes (red represents upregulated genes, and blue represents downregulated genes).

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