Fig. 7: Metabolomics of ADA2-deficient cells.
From: ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances
A Tracer metabolomics after 24 h incubation in RPMI medium containing 13C-glucose. The analysis shows ADA2WT/WT (n = 1) and ADA2-/- (n = 3) U-937 cells. B Tracer metabolomics were performed in healthy control (HC) (n = 1) and DADA2 (n = 1) human monocyte-derived macrophages after 24 h incubation in RPMI medium containing 13C-glucose. The bar graphs show the average fraction of isotopologues over the three replicates. The x-axis indicates the number of labelled C atoms in the respective molecule.
