Fig. 1: Salinomycin treatment promoted apoptotic cell death.
From: Salinomycin as a death switch: how gastric cancer cells choose their demise
Scatter plots following 48 h of Sal treatment of different GC cell lines analyzed by flow cytometry, using Annexin V-FITC and PI labeling. Representative dot plots present the percentage of live cells in the lower-left quadrant, early apoptotic cells in the lower-right quadrant, late apoptotic cells in the upper-right quadrant and necrotic cells in the upper-left quadrant. Histogram reports frequencies of apoptotic and necrotic cells as ratios of Sal-treated to vehicle for each tested cell line. Sal significantly promoted apoptosis in two out of 4 cell lines. Data were obtained from three independent biological replicates. One-sample t-test was used to evaluate statistical significance (*p < 0.05; **p < 0.01).
