Fig. 2: Cadherin-26 (CDH26) localizes to the apical membrane.
From: Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity
a Immunofluorescence for E-cadherin (green), CDH26 (red), acetylated tubulin (Ac-tubulin, blue) and nuclei (aqua) in fresh tissue samples obtained from human tracheas. Bottom panels of A (indicated by white arrows): zoomed into regions showing that CDH26 is non-junctional and predominantly in the apical membrane of cells. b Localization of CDH26A is maintained in AECs grown at ALI for at least 3 week in culture. Images are from a single donor and representative of the localization pattern of CDH26 from a survey of four different donors. Z-stack in B:zoomed region showing apical localization in cultured AECs, regions indicated by white arrows. Scale bar = 10 µm.
