Fig. 3: Structural basis for SIKE1 CC2 alone and SIKE1 CC2-STRN3 complex.
From: Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling
a Cartoon views of the overall structure of apo SIKE1 CC2. Four chains of SIKE1 CC2 are colored cyan (chain A), palecyan (chain B), blue (chain A′), and lightblue (chain B′), respectively. b Interactions at the dimeric interface of SIKE1 CC2. c Interactions at the tetrameric interface of SIKE1 CC2. d Cartoon views of the overall structure of SIKE1 CC2-STRN3 complex. The two SIKE1 CC2 molecules are colored cyan (chain A) and palecyan (chain B), respectively, and the STRN3 peptides are colored yellow. e, f Zoomed-in views of SIKE1 and STRN3 interactions at the complex interface. The red dash lines represent hydrogen bonds or salt bridges. The interface residues are labeled and highlighted by the stick model
