Fig. 9: STRIPAK regulates Hippo signaling dependent on complex assembly.
From: Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling
a Proposed model of the topological structure of the STRIPAK complex. b Real-time PCR analysis of expression levels of CTGF in HGC-27 cells transfected with the indicated plasmids. e.v., empty vector; WT, wildtype; Δ64–190, deletion of residues 64–190; Δ796–837, deletion of residues 796–837; 3LD, L15D/L19D/L36D; 4M, E96A/R109A/A100D/M105E; 4LD, L182D/L186D/L189D/L193D. c Cell proliferation rate of HGC-27 cells transfected with the indicated plasmids (day 3). Bar graphs represent the means ± SD. Experiments were repeated three times. Unpaired t tests were used to compare the difference between the two groups. *Significant relative to the control or the wildtype group, p < 0.05, **p < 0.01, ***p < 0.001. n.s., no statistical significance
