Table 2 Neutralization activity of AF4H1L1, AF4H1K1, and AF4H1/FI6L against a panel of IAVs from different groups
Groups | Subtypes | Virus strains | Abbreviations | Neutralization titer with different MAbs (IC50, μg/ml) | |||
|---|---|---|---|---|---|---|---|
AF4H1L1 | AF4H1K1 | AF4H1/FI6v3L | |||||
Group 2 | H3-clade | H3N1 | H3(A/Aichi/2/1968)/PR8-RG | H3-rAC/68 | > 200a | 138.0 | ND |
H3N2 | A/Jiangxi//262/2005 | H3-JX/05 | > 200 | 26.5 | 23.2 | ||
H4N1 | H4(A/duck/Czech/1956)/PR8-RG | H4-rCZ/56 | > 200 | 189.0 | 150.0 | ||
H14N5 | A/mallard duck/Astrakhan/263/1982 | H14-AS/82 | > 200 | 13.2 | 16.7 | ||
H7-clade | H7N9 | A/Anhui/1/2013 | H7-AH/13 | > 200 | > 200 | 71.1 | |
H10N8 | A/Jiangxi-Donghu/346/2013 | H10-JX/13 | > 200 | > 200 | 66.9 | ||
H15N8 | A/duck/Australia/341/1983 | H15/AU/83 | > 200 | > 200 | > 200 | ||
Group 1 |  | H1N1 | A/California/04/2009 | H1-CA/09 | > 200 | > 200 | > 200 |
H2N3 | A/environment/Guangdong/2/2009 | H2-GD/09 | > 200 | > 200 | > 200 | ||
H5N1 | A/bar-headed goose/Qinghai/1/2005 | H5-QH/05 | > 200 | > 200 | > 200 | ||
H9N2 | A/chicken/Beijing/2/1997 | H9-BJ/97 | > 200 | > 200 | > 200 | ||
