Fig. 2: Human SIRT3 is an efficient H3K9bhb eraser.
From: Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3
a ITC fitting curves of several human sirtuin proteins titrated with H31-15K9bhb peptide. N.D. not detected. b–d MALDI-TOF MS (b), RP-HPLC (c), and dot-blot (d) based deacylation assays of SIRT3 with H3K91–15K9bhb peptide as substrate. e Schematic diagram of the de-β-hydroxybutyrylation reaction catalyzed by SIRT3
