Fig. 1: Phylogenetic analysis of 26 animals based on ACE2 and characteristics of the SARS-CoV-2 RBD-binding residues of ACE2s.
From: Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2
Phylogenetic tree based on ACE2 amino acid sequences was generated using MEGA X. The 27 species (including human) belonging to 11 orders are shown in the right column. 20 residues of hACE2 which are crucial in interacting with the SARS-CoV-2 RBD are listed. Red letters indicate the substitutions in the ACE2 of 26 animal species.
