Fig. 2: Deep whole-genome sequencing and genetic variation among the patients. | Cell Discovery

Fig. 2: Deep whole-genome sequencing and genetic variation among the patients.

From: Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility

Fig. 2: Deep whole-genome sequencing and genetic variation among the patients.

a Sequencing depth distribution. b Proportions and numbers of types (SNP, Indel) of genetic variants identified from the patients. c Proportions and numbers of functional consequences of the genetic variants among the patients. d Pedigree gene discovery. GOLGA3 and DPP7 were marked in bold for presence of rare recurrent loss of function variants. e Mutation burden association test for loss of function between the severe and non-severe patients. f Allele frequency distribution for all the missense and loss of function variants present in ACE2 and TRMPSS2 genes.

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