Fig. 1: YTHDF3 selectively binds to m1A-carrying RNA. | Cell Discovery

Fig. 1: YTHDF3 selectively binds to m1A-carrying RNA.

From: Cytoplasmic m1A reader YTHDF3 inhibits trophoblast invasion by downregulation of m1A-methylated IGF1R

Fig. 1

a Illustration of the m1A-modified RNA probe with stem and loop structure derived from the known m1A 1322 site in human 28S rRNA. Red asterisks indicated the m1A-modified sites. b Dot-blot analysis of the m1A probes specificity with m1A or m6A antibody. c IP and immunoblot analyses of the indicated probes in trophoblast HTR8/SVneo transfected with YTHDF1/2/3 plasmid as indicated. Data are representative of three independent experiments.

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