Fig. 5: The intraocular metagenome in the eyes of rabbit, rat, macaque, and pig analyzed using PCoA.

a The PCoA of intraocular metagenomes in four mammals. The Bray Curtis distance was used and P value was calculated using PERMANOVA test. b The abundance of bacterial DNA in rat intraocular fluids was measured using real-time PCR assays of total 16S rDNA and represented as the relative abundance to the level of rat Actb gene. c The abundance of P. acnes DNA in rat intraocular fluids was measured using real-time PCR assays of P. acnes 16S rDNA and represented as the relative abundance to the level of rat Actb gene. The error bar represents the mean ± SEM. The statistical difference was measured using Mann-Whitney U test and the significance levels are denoted by asterisks (*P < 0.05, **P < 0.01, NS: not significant).