Fig. 4: Landscape of transcriptome in human embryo-like structures from blastoids on day 8 and day 10.
From: Generation of human blastocyst-like structures from pluripotent stem cells
a–d Immunofluorescence staining of EPI marker OCT4 and PE marker GATA6 in Day 8 (a) and Day 10 (b) embryonic structures. A UMAP plot analysis revealed 5 clusters in embryonic structures on day 8 (c) and day 10 (d), identified with assigned cluster names. e UMAP projection of integrated datasets showing our results of embryonic structures on day 8, day 10, and previous studies32,33 (data of 7–14 d.p.f.). f Heatmap of lineage-specific genes overlapped between a previous study32 (data of 7–14 d.p.f. embryos) and this study on days 8 and 10.
