Table 2 Sperm characteristics and flagellar morphology of Wdr63-KO male mice.

From: Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly

 

WT

KO

Semen parameter

 Motility (%)

77.79 ± 8.24

4.83 ± 3.38**

 Progressive (%)

40.66 ± 10.30

0.71 ± 0.99**

Sperm flagellar morphologya

 Absent flagella (%)

4.05 ± 1.48

21.5 ± 1.49*

 Short flagella (%)

0 ± 0

25.84 ± 5.59**

 Coiled flagella (%)

0 ± 0

29.12 ± 5.72**

 Irregular caliber (%)

1.53 ± 0.63

17.03 ± 1.86**

 Bent flagella (%)

3.15 ± 1.09

6.51 ± 1.02

  1. aData represent the means ± SD of three independent experiments.
  2. *P < 0.05, **P < 0.01.