Fig. 5: Dysregulation of genes can be partially rescued by NAD+ supplementation.
From: Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models
a–e qPCR results of relative expression levels of PARP family members as listed. Parp1 (a), Parp2 (b), Parp9 (c), Parp10 (d), and Parp14 (e). f–j qPCR results of relative expression levels of NAD+ salvage pathway-related genes, Nmnat1 (f), Nmnat2 (g), Nmnat3 (h), Nampt (i), and Naprt (j). k–o qPCR results of relative expression levels of three NAD+ de novo synthesis-related genes, Haao (k), Ido1 (l), and Kmo (m), and two nucleoside transporter genes, Slc25a51 (n) and Slc29a1 (o). p, q qPCR results of relative expression levels of CD400 receptor genes, Cd200r3 (p) and Cd200r4 (q). r qPCR results of relative expression levels of apoptosis protease activating factor gene, Apaf1. All quantification data are shown as means ± SEM, t-test. n = 3 mice for each group. Exact P values are indicated.
