Fig. 3: Comparison of transcriptomic profiles among iNKT cells from different peripheral organs. | Cell Discovery

Fig. 3: Comparison of transcriptomic profiles among iNKT cells from different peripheral organs.

From: Single-cell analysis reveals differences among iNKT cells colonizing peripheral organs and identifies Klf2 as a key gene for iNKT emigration

Fig. 3: Comparison of transcriptomic profiles among iNKT cells from different peripheral organs.The alternative text for this image may have been generated using AI.

a–c UMAP plots from 10X genomics scRNA-Seq dataset from sorted liver iNKT cell(a), spleen iNKT cell (b), and Lymph node iNKT cells (c) (left). Violin plots showing the top two cluster-specific signatures in iNKT cells from liver (a), spleen (b), and lymph node (c). d Pearson correlation matrix of the average expression profiles based upon all differentially expressed genes from all indicated subpopulations analyzed. e Gene list showing significant change of iNKT1 signatures among iNKT cells from thymus, liver, spleen, and lymph node, extracted from (d).

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