Fig. 3: Cmpk2 is expressed in mouse neurons. | Cell Discovery

Fig. 3: Cmpk2 is expressed in mouse neurons.

From: Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Fig. 3: Cmpk2 is expressed in mouse neurons.The alternative text for this image may have been generated using AI.

a In situ hybridization of Cmpk2 expression in adult mouse brain sagittal sections. b Enlarged view of Cmpk2 expression in the hippocampus, thalamus, and cerebellum; DAPI (blue) staining of nuclei. c, d Dual in situ hybridization of Cmpk2 (red) with the glutamatergic neuronal marker Vglut2 (green) in the mouse thalamus (c) and dentate nuclei of the cerebellum (d). e, f Dual in situ hybridization of Cmpk2 (red) with the GABAergic neuronal marker Gad1 (green) in the mouse thalamus (e) and the PCL of the cerebellum (f). g, h Double fluorescence labeling of Cmpk2 (red) and the astrocytes marker S100β (green) in the thalamus (g) and DG of hippocampus (h). Ctx cortex, Hip hippocampus, Thal thalamus, Crb cerebellum, DG dentate gyrus, PCL Pukinje cell layer, GCL granule cell layer. Scale bars, 500 μm in a; 50 μm in b–h.

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