Fig. 2: Profiling of PBMCs by scRNA-seq and scV(D)J-seq. | Cell Discovery

Fig. 2: Profiling of PBMCs by scRNA-seq and scV(D)J-seq.

From: Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling

Fig. 2

a Schematic diagram showing the experimental design for scRNA-seq and scV(D)J-seq. PBMCs were collected from 12 participants. b Humoral immune responses (sVNT) of each sample at Day0, Day3, Day14, Day90 and Day180 in PrSV group (top) and InaV group (bottom), respectively. c UMAP representation of PBMCs from all participants and time points sampled (top), and UMAPs annotated by time point separately (bottom). Cell types were identified by cluster gene signatures and color-coded. Each dot represents an individual cell. d UMAP projection of canonical markers of each cell type.

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