Fig. 3: SARS-CoV-2 GFP/ΔN variants can infect Sftpc-hACE2-NF/F mice.

a, c, e H&E staining shows the pathological changes in Sftpc-hACE2-NF/F mouse lung after infection with SARS-CoV-2 GFP/ΔN Alpha (a), Beta (c), Gamma (e) variants. The dark frame blocks were magnified on the right. b, d, f Immunofluorescence staining of mouse lungs for SARS-CoV-2 GFP/ΔN GFP protein (green), and DAPI (blue).