Fig. 4: Stabilization of the Clr6 in the SIN3L or SIN3S complex.
From: Two assembly modes for SIN3 histone deacetylase complexes
a The interactions between Clr6 and the HID of Pst1/2/3. The HID1 and HID2 interact with the Clr6 conservatively. The Clr6 is shown in surface, while Pst1, Pst2 and Pst3 are shown in cartoon. b, c Close-up views of the interface between Clr6 and HID1 (b) or HID2 (c). d The sequence alignment of Sin3 homologs from different species. sp, Schizosaccharomyces pombe; sc, Saccharomyces cerevisiae; ce, Caenorhabditis elegans; dm, Drosophila melanogaster; hs, Homo sapiens; mm, Mus musculus; at, Arabidopsis thaliana. e, f Clr6 is stabilized by the scaffold of the SIN3L (e) or the SIN3S (f) complex.
