Fig. 7: Upregulation of leg1b in leg1azju1/zju1 is not coupled with an enrichment of H3K4me3 around its TSS. | Cell Discovery

Fig. 7: Upregulation of leg1b in leg1azju1/zju1 is not coupled with an enrichment of H3K4me3 around its TSS.

From: Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner

Fig. 7

a Graph showing the normalized reads distribution profiles of the genome-wide H3K4me3 enrichment (RPKM) in the liver dissected from WT, leg1a_mu, upf3a_mu and upf3a;leg1a_dm embryos at 5 dpf. TSS, transcription start site. b–e Genome browser view of the H3K4me3 enrichment in the genomic region of representative liver-specific (b), muscle-enriched (c), intestine-enriched genes (d) and leg1a and leg1b (e) genes. The y axis shows the ULI-NChIP counts across the genomic region shown.

Back to article page