Table 1 Differences in HA1 amino acid sequences between HPAI H5 virus derived from humans and avians.
Host | Isolation | Mutation |
|---|---|---|
Human | A/Astrakhan/3212/2020 | H5N8 | Reference sequence |
Human | A/England/215201407/2021 | H5N1 | A144T |
A/Hunan/10117/2021 | H5N6 | T192I | |
A/Colorado/18/2022 | H5N1 | L108M, V214A | |
Avian | A/Brown-headed Gull/Tibet/XZ19/2021 | H5N8 | H277N |
A/chicken/Korea/H001/2021 | H5N8 | Q19R | |
A/common teal/Ningxia/105/2020 | H5N8 | V214I | |
A/whooper swan/Shanxi/4-1/2020 | H5N8 | T192I | |
A/Cygnus columbianus/Hubei/49/2020 | H5N8 | T192I | |
A/goose/Guangdong/S4751/2021 | H5N6 | E130D | |
A/American wigeon/North Carolina/AH0182517/2022 | H5N1 | L108M, V214A | |
A/Phasianus colchicus/Belgium/294/2022 | H5N1 | Q19K | |
A/stork/Spain/442-8 22VIR2142-12/2022 | H5N1 | Q19K | |
A/mute swan/Croatia/6/2022 | H5N1 | S124N | |
A/Caspian gull/Netherlands/1/2022 | H5N1 | V152L | |
A/chicken/England/002070/2022 | H5N1 | V152L | |
A/turkey/Netherlands/21020942-001005/2021 | H5N8 | No mutation | |
A/chicken/Krasnodar/334-01/2021 | H5N8 | No mutation | |
A/pheasant/Scotland/000348/2021 | H5N1 | No mutation | |
A/chicken/Nigeria/VRD21-43 21VIR2288-4/2021 | H5N8 | R173Q |
