Fig. 7: Establishment of a population-specific BCDG germline mutation prediction model. | Cell Discovery

Fig. 7: Establishment of a population-specific BCDG germline mutation prediction model.

From: Comprehensive genomic profiling of breast cancers characterizes germline-somatic mutation interactions mediating therapeutic vulnerabilities

Fig. 7: Establishment of a population-specific BCDG germline mutation prediction model.The alternative text for this image may have been generated using AI.

a Workflow of establishing predictive models for BCDG mutation and two-hit inactivation. b ROC curves of the BCDG mutation prediction model in the training set (red) and validation set (blue). c Calibration plots of the predicted and actual probabilities of the BCDG mutation model in the training set (red) and validation set (blue). d ROC curves of the two-hit inactivation prediction model in the training set (red) and validation set (blue). e Calibration plots of the predicted and actual probabilities of the two-hit inactivation model in the training set (red) and validation set (blue).

Back to article page