Fig. 2: Clinical trial scheme and demographic and clinical characteristics of the enrolled patients.

a The treatment scheme showing the enrolled patients who underwent leukapheresis and then received lympho-depleting chemotherapy. After CAR-T products were successfully manufactured, patients were treated with CAR-T cells. The efficacy and toxicity were monitored during follow-up. b Flow diagram describing numbers of patients enrolled in this clinical trial. Enrollment occurred to obtain peripheral blood for manufacture of the CAR-T products and then the prospective patients were required to meet eligibility to infuse CAR-T cells.