Fig. 1: Design and workflow for studying osteoporosis and its subtypes on the basis of a multi-omics atlas generated by data-intensive analysis. | Cell Discovery

Fig. 1: Design and workflow for studying osteoporosis and its subtypes on the basis of a multi-omics atlas generated by data-intensive analysis.

From: Multi-modal molecular determinants of clinically relevant osteoporosis subtypes

Fig. 1: Design and workflow for studying osteoporosis and its subtypes on the basis of a multi-omics atlas generated by data-intensive analysis.

a The study design and workflow in the principle of data-intensive analysis. b The global view of the molecular landscape of osteoporosis. The landscape consists of different data domains. (1) The BMD related indices such as FN BMD and TH BMD. (2) The clinical indicators such as age, gender and prior fracture. (3) The normalized expression of multi-omics including microbiota, metabolite and methylation CpG. (4) The global characteristics of SNPs as the top five principal components.

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