Fig. 6: Genome characteristics underlying multi-modal molecular signatures M3S of osteoporosis subtypes in a Yin-Yang scheme. | Cell Discovery

Fig. 6: Genome characteristics underlying multi-modal molecular signatures M3S of osteoporosis subtypes in a Yin-Yang scheme.

From: Multi-modal molecular determinants of clinically relevant osteoporosis subtypes

Fig. 6: Genome characteristics underlying multi-modal molecular signatures M3S of osteoporosis subtypes in a Yin-Yang scheme.

a Global SNV patterns of osteoporosis subtypes. b Protein association network among global snpGenes. c Functional enrichment of global snpGenes. d Preferences of SNV types of xQTL SNPs corresponding to different osteoporosis subtypes. e Shared and specific local snpGenes among different QTLs from xQTL model. f Yin-Yang osteoporosis subtypes characterized by the subtype-specific genotype-molecular phenotype associations. g Allele frequency of representative Calcium related genes. h Methylation differences between CISs, with the cases of a few Calcium and osteoporosis-related genes.

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