Fig. 4: Conformational differences of MCH recognition by MCHR1 and MCHR2. | Cell Discovery

Fig. 4: Conformational differences of MCH recognition by MCHR1 and MCHR2.

From: Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors

Fig. 4: Conformational differences of MCH recognition by MCHR1 and MCHR2.

a Structural superposition of MCH-bound MCHRs, presented from both side-view (the left) and top view (the right). b, c Mesh representations of MCH within the binding pockets of MCHR1 and MCHR2. d, e The differential interactions between MCH and MCHRs, focusing on R11 (d) and the C7, M8, and R14 residues of MCH (e).

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