Fig. 2: DNA and AMPPNP recognition in the E5-ssDNA-AMPPNP complex. | Cell Discovery

Fig. 2: DNA and AMPPNP recognition in the E5-ssDNA-AMPPNP complex.

From: Structural and functional insights into the helicase protein E5 of Mpox virus

Fig. 2

a Overall folding and assembly of MPXV E5 in the complex structure. b Conformations of DNA and SF3 helicase domains in the complex structure. DNA and the bound AMPPNP are shown as spheres. c The detailed interactions between DNA and residues from the DIL loops of SF3 helicase domains. d, e AMPPNP recognition by the SF3 helicase domains. Mg2+ ion is shown as sphere in black.

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