Fig. 2: Tfh and activated non-follicular T cells have a distinct transcriptome. | Cell Discovery

Fig. 2: Tfh and activated non-follicular T cells have a distinct transcriptome.

From: Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue

Fig. 2: Tfh and activated non-follicular T cells have a distinct transcriptome.

a Volcano plot of all significantly DEGs between Tfh and activated non-follicular T cells. A selection of Tfh-specific and non-follicular T cell-specific genes are labeled. Genes with adjusted P values of less than 0.05 were considered significant and are represented in red. b Heatmap of the most significantly DEGs between the two cell populations, with the genes matching the ImmPort immune gene list labeled. c GSEA of our Tfh datasets against publicly available datasets of Tfh samples (GSE134153). The Normalized Enrichment Score (NES) of both samples with a significant adjusted P value of less than 0.05 is shown.

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