Fig. 6: Clinical trial of VEGFR blockade combined with anti-PD1 therapy in systemically metastasized CoM patients. | Cell Discovery

Fig. 6: Clinical trial of VEGFR blockade combined with anti-PD1 therapy in systemically metastasized CoM patients.

From: Single-cell sequencing depicts tumor architecture and empowers clinical decision in metastatic conjunctival melanoma

Fig. 6

a Chronologic changes in the radiology of patient CoM-10 treated with VEGFR blockade combined with anti-PD1 therapy. b Diagram of CoM progression and treatment for patient CoM-11. The tumor was confirmed to recur and progress rapidly. With VEGFR blockade combined with anti-PD1 therapy, no progression was observed. c Chronologic changes in the tumor burden of patients. d Schematic drawing of the likely underlying mechanisms of the clinical trial.

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