Fig. 1: Characterization of IFN-independent multi-organ inflammation in RelB−/− mice. | Cell Discovery

Fig. 1: Characterization of IFN-independent multi-organ inflammation in RelB−/− mice.

From: NF-κB RelB suppresses the inflammatory gene expression programs of dendritic cells by competing with RelA for binding to target gene promoters

Fig. 1: Characterization of IFN-independent multi-organ inflammation in RelB−/− mice.

a Representative image of IFNAR−/−RelB−/− mouse (right) and IFNAR−/− littermate (left) at 4 weeks of age; ruler for scale. b Representative image of thymi from IFNAR−/−RelB−/− mouse (right) and IFNAR−/− littermate (left). c Thymic weights from age-matched WT (dark blue), RelB−/− (dark red), IFNAR−/− (light blue, checkered), IFNAR−/−RelB−/− (light red, checkered) mice. ***P < 0.001, **P < 0.01, *P < 0.05; error bars indicate SD. Statistical analysis was done using an unpaired two-tailed Student’s t-test. d, e Representative images of hematoxylin and eosin (H&E)-stained sections of WT, RelB−/−, IFNAR−/−, and IFNAR−/−RelB−/− mouse lungs (d) and livers (e). n = 3–4.

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