Fig. 5
From: Structures of the human spliceosomes before and after release of the ligated exon
Structural rearrangements during the ILS1-to-ILS2 transition. a Overall structural changes during the ILS1-to-ILS2 transition. The mobile protein components in the transition are color-coded to highlight the structural changes. Immobile proteins are shown in gray. In the transition, Prp43 is recruited into ILS2. b A close-up view on select regions of the ILS1 and ILS2 complexes. Two orientations are shown. c A close-up view on the transition from ILS1 to ILS2
