Fig. 1 | Cell Research

Fig. 1

From: Antiviral immunity: a link to bile acids

Fig. 1

BA-TGR5-GRK-β-arrestin-SRC axis promotes antiviral immune response. Immediate-early activation of NF-κB induced by virus infection promotes intracellular accumulation of BAs. BAs then activate the TGR5-GRK-β-arrestin-SRC signaling and facilitate activation of multiple innate antiviral signaling components, which finally enhance antiviral immune responses

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