Fig. 6: Working model.
From: Regulation of sister chromatid cohesion by nuclear PD-L1
Sororin suppresses WAPL and maintains sister chromatid cohesion in Sororin cohesin cells. In contrast, in PD-L1 overexpressed cells, PD-L1 compensates for the loss of Sororin and competes with WAPL binding to PDS5B, thereby regulating sister chromatid cohesion.
